Author: Dr. Malireddy S Reddy Abstract This review/research article is written to explain in detail the pathophysiology of the chronic stress syndrome, which will ultimately leads to several diseases. Panic circumstances under which this chronic stress syndrome develops and induces anxiety, fear and diseases are thoroughly outlined. The negative effects of the chronic-low-level stress on the gastro intestinal tract and its micro flora, including Probiotics, have been presented with explicit details. The positive effects of meditation on curbing the stress and stress related diseases have been discussed, particularly with reference to the effect of meditation on controlling or modulating the stress inducing hormones. Keywords: Fight or flight response; Stress; Chronic-low-level stress; Stress syndrome; Meditation; Probiotics; Obesity; Hypertension; MS Reddy's Multiple Mixed Strain Probiotic Therapy. Introduction This article...