Juniper Publishers-Open Access Journal of Toxicology

Open Access Journal of Toxicology Background The term 'aerotoxic syndrome' was coined in 2000 [ 1 ] to describe a collection of predominantly neurological and respiratory signs and symptoms found in some commercial aircrew, which includes pilots and cabin crew. From the 1950's, aircraft were redesigned to provide pressurized cabin air directly from the compressor stage of the engine, known as bleed air. This allowed for the fuel consuming turbo compressors used prior to that date to be dispensed with. However, it also led to the exposure of aircrew and passengers to fugitive emissions from aircraft engines. This bleed air remains, to date, supplied to the cabin unfiltered. Gas turbine engines require the use of vapors-phase lubricants, including additives, which can withstand the extremely high operating temperatures and pressures found in normal use. The most widely used anti-wear additive is tri- cresylphosphate (TCP), an organophosphate compound ...

Open Access Journal of Toxicology Abstract The biosynthesis of nano particles with a great deal of effort by using a 'Green technology' that gives an innocuous, inexpensive and environmental friendly approach has been widely used. The technology also leads to fabricate wonder materials for biomedical applications. The in vitro green approaches for the reduction of metal ions furnishes a flexible method to obtain nano particles with control over their size and shape that can be attributed to the flexibility of changing the medium pH and reaction temperature. This review provides an outlook on a range of devices and tools that can make a system for detection of a therapeutic agent and to determine its action on an intended target, facilitating the research in diagnosis and prevention of cancer. The validation of nano particles with these exciting approaches may serve a strong foundation for modified chemotherapies in the next phase of clinical trials which...