Rare Presentation of Amyotrophic Lateral Sclerosis as Frontotemporal Dementia: A Case Report-Juniper Publishers


JUNIPER PUBLISHERS- OPEN ACCESS JOURNAL OF TOXICOLOGY

Rare Presentation of Amyotrophic Lateral Sclerosis as Frontotemporal Dementia: A Case Report


Authored by Ali Mahmood Khan

Abstract

Amyotrophic Lateral Sclerosis is also known as motor neuron disease or Lou Gehrig's disease. It mainly involves neurons which control voluntary functions. It is characterized by weakness and atrophy of muscles. It can also cause death by respiratory failure. Our case is a 53-years old female with Frontotemporal dementia (FTD), who after two years of stay at a psychiatric facility manifested symptoms of Amyotrophic Lateral Sclerosis (ALS). The patient stayed four and a half years in the hospital, mostly in the psychiatric facility. We have discussed the course of her illness as it progressed, to describe the surprising association between ALS and FTD. A good deal of research has been conducted in this context in the past decades. Genetic, biochemical and clinical associations between the two conditions have been discussed in the later part of this report.

This study is aimed is to study the relationship between Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal dementia (FTD). There have been genetic and biochemical linkages found between the two conditions. ALS usually manifests with the symptoms of frontotemporal dysfunction syndromes or preceding them. However, there have been instances where ALS begins in the final stages of frontotemporal dementia.

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