Wishing you Merry Christmas

May Christmas bring joy to your heart and happiness to your home.  Wishing you a magical and blissful holiday.

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Chronic Stress-An Etiological Agent for the Genesis of Multitude of Diseases, and the Effect of Meditation on Modulating the Stress-Juniper publisher

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Author: Dr. Malireddy S Reddy Abstract This review/research article is written to explain in detail the pathophysiology of the chronic stress syndrome, which will ultimately leads to several diseases. Panic circumstances under which this chronic stress syndrome develops and induces anxiety, fear and diseases are thoroughly outlined. The negative effects of the chronic-low-level stress on the gastro intestinal tract and its micro flora, including Probiotics, have been presented with explicit details. The positive effects of meditation on curbing the stress and stress related diseases have been discussed, particularly with reference to the effect of meditation on controlling or modulating the stress inducing hormones. Keywords: Fight or flight response; Stress; Chronic-low-level stress; Stress syndrome; Meditation; Probiotics; Obesity; Hypertension; MS Reddy's Multiple Mixed Strain Probiotic Therapy. Introduction This article...
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Transdermal Methimazole for Feline Hyperthyroidism

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 Open Access Journal of Toxicology  Introduction Over the past 20 years, the prevalence of feline hyperthyroidism has increased astoundingly [1-3]. It has become the most common endocrine disorder in cats, and the risk worsens with each year of increasing age, being most common in middle to older-aged felines [1]. The disease is primarily characterized by an excessive production and release of the thyroid hormones thyroxine (T4) and triiodothyronine (T3) most commonly due to a functional, benign adenomatous hyperplasia of the thyroid gland. At present, there is not a feline specific thyroid stimulating hormone (TSH) assay test available, therefore unlike human hyperthyroid diagnosis, veterinarians do not commonly depend on a low TSH value for primary hyperthyroid diagnosis. Hyperthyroidism diagnosis in cats is generally based on a high free T4 level and the presence of clinical signs and symptoms. Some of the clinical complications of hyperthyroidism that may be p...
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Crotalus lepidus lepidus Venom Produces Hemolysis and Lipid Peroxidation in Human Erythrocytes in vitro

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Author : Alejandro Zugasti-Cruz Abstract The hemolytic and lipid peroxidative effects of crude venom from Crotalus lepidus lepidus, a rattle snake found in the Northeast of Mexico and southeast of the United States, were investigated in human erythrocytes in vitro. Significant concentration-dependent effects were found on both hemolysis (evaluated as release of hemoglobin) and lipid peroxidation (as a common index of oxidative damage to membrane lipids) in the red blood cells. These results suggest that hemolysis was produced with the involvement of oxidative stress as a potential mechanism of toxicity in the erythrocytes. Keywords: Hemolysis; Lipid Peroxidation; Crotalus lepidus lepidus Venom Abbreviations: TBA: Thiobarbituric Acid; TCA: Trichloroacetic Acid; MDA: Malondyaldehide; (C.l. lepidus): Crotalus Lepidus Lepidus Introduction Snake venoms are among the best pharmacologically characterized natural toxins, chiefl...
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